Van Dusen is a surname. Notable people with the surname include:
Chris Van Dusen, American television writerClyde Van Dusen (1885–1951), American jockey and Thoroughbred racehorse trainerClyde Van Dusen (horse) (1926–1948), American Thoroughbred racehorseFrancis Lund Van Dusen (1912–1993), American judgeFred Van Dusen (born 1937), American baseball playerGeorge W. Van Dusen (1826–?), American businessmanGranville Van Dusen (born 1944), American actorH.V. Van Dusen (died 1903), American civil servant and Los Angeles city council memberJulie Van Dusen, Canadian journalistWillis Van Dusen, American mayor