Van Benthem is a Dutch surname meaning "from Bentheim". It can refer to:
Evert van Benthem (b. 1958), Dutch speedskater, twice winner of the ElfstedentochtJean Van Benthem (fl. 1908), Belgian cyclistJohan van Benthem (b. 1949), Dutch professor of logicJohannes Bob van Benthem (1921-2006), Dutch lawyer, first president of the European Patent OfficeMerle van Benthem (b. 1992), Dutch off-road bicycle racerRoland van Benthem (b. 1968), Dutch politician