Van Acker is a surname. Notable people with the surname include:
Achille Van Acker (1898–1975), Belgian politician and Prime Minister of BelgiumCharles Van Acker (1912–1998), Belgian-American racecar driverDrew Van Acker (born 1986), American actorEvi Van Acker (born 1985), Belgian sailorJohannes Baptista van Acker (1794–1863), Flemish painterLuc Van Acker (born 1961), Belgian musician, producer and label managerRegi Van Acker (born 1955), Belgian footballer and coachThibaut Van Acker (born 1991), Belgian footballer