Van Acker is a surname. Notable people with the surname include:
Achille Van Acker (1898–1975), Belgian politician and Prime Minister of Belgium
Charles Van Acker (1912–1998), Belgian-American racecar driver
Drew Van Acker (born 1986), American actor
Evi Van Acker (born 1985), Belgian sailor
Johannes Baptista van Acker (1794–1863), Flemish painter
Luc Van Acker (born 1961), Belgian musician, producer and label manager
Regi Van Acker (born 1955), Belgian footballer and coach
Thibaut Van Acker (born 1991), Belgian footballer
