Harman Patil (Editor)

VU 0238429

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PubChem CID
  
42633508

Molar mass
  
351.276 g/mol

ChEMBL ID
  
466253

Formula
  
C17H12F3NO4

Pubchem
  
42633508

ChemSpider ID
  
24606034

VU-0238429 httpsuploadwikimediaorgwikipediacommonsthu

3D model (Jmol)
  
Interactive image Interactive image

VU-0238429 is a drug which acts as a selective positive allosteric modulator for the muscarinic acetylcholine receptor M5. It was the first selective ligand developed for the M5 subtype, and is structurally derived from older M1-selective positive allosteric modulators such as VU-0119498. Replacing the O-methyl- by a phenylgroup further improves the receptor subtype selectivity (VU-0400265).

References

VU-0238429 Wikipedia
(Text) CC BY-SA