Entrez 79679 | Ensembl ENSG00000134258 | |
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Aliases VTCN1, B7-H4, B7H4, B7S1, B7X, B7h.5, PRO1291, VCTN1, V-set domain containing T cell activation inhibitor 1 External IDs MGI: 3039619 HomoloGene: 11627 GeneCards: VTCN1 | ||
V-set domain-containing T-cell activation inhibitor 1 is a protein that in humans is encoded by the VTCN1 gene.
Function
B7H4 belongs to the B7 family (see CD80; MIM 112203) of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands (e.g., CD28; MIM 186760) on T lymphocytes.[supplied by OMIM]
B7-H4 is an immune checkpoint molecule.
References
VTCN1 Wikipedia(Text) CC BY-SA