Ussher is a surname. Notable people with the surname include:
Beverley Ussher (d. 1908), Australian residential architectElizabeth Tyrrell (née Ussher) (1619-1693), daughter of James UssherHenry Ussher (d. 1613), Archbishop of ArmaghHerbert Taylor Ussher, Governor of Tobago 1872-1875James Ussher (1581-1656), Irish archbishop and theologianJane Ussher, New Zealand photographerJohn Ussher (died 1741), Irish MPJohn Ussher (1703–1749), Irish MPJohnny Ussher (1830-1879), Canadian frontiersmanKitty Ussher (born 1971), British Labour Member of ParliamentRichard J. Ussher (1841-1913), Irish ornithologistSt George Ussher (d. 1775), later St George St George, 1st Baron St George