EC number 1.1.1.154 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 62213-62-1 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, an ureidoglycolate dehydrogenase (EC 1.1.1.154) is an enzyme that catalyzes the chemical reaction
(S)-ureidoglycolate + NAD(P)+The 3 substrates of this enzyme are (S)-ureidoglycolate, NAD+, and NADP+, whereas its 4 products are oxalureate, NADH, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S)-ureidoglycolate:NAD(P)+ oxidoreductase. This enzyme participates in purine metabolism.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1WTJ and 1XRH.
References
Ureidoglycolate dehydrogenase Wikipedia(Text) CC BY-SA