Routes of
administration oral CAS Number 107736-98-1 Molar mass 512.64 g/mol ChemSpider ID 59311 | ATC code none PubChem CID 65902 Pubchem 65902 | |
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Legal status In general: uncontrolled Biological half-life Unknown but effects last much longer than other azapirones, up to 23 hours after a single dose in human clinical studies. | ||
How to pronounce umespirone
Umespirone (KC-9172) is a drug of the azapirone class which possesses anxiolytic and antipsychotic properties. It behaves as a 5-HT1A receptor partial agonist (Ki = 15 nM), D2 receptor partial agonist (Ki = 23 nM), and α1-adrenoceptor receptor antagonist (Ki = 14 nM), and also has weak affinity for the sigma receptor (Ki = 558 nM). Unlike many other anxiolytics and antipsychotics, umespirone produces minimal sedation, cognitive/memory impairment, catalepsy, and extrapyramidal symptoms.
References
Umespirone Wikipedia(Text) CC BY-SA