USS Columbia may refer to:
A 44-gun frigate Columbia was under construction in 1814 but burned to prevent capture by the British
USS Columbia (1836) was a 50-gun sailing frigate launched in 1836 and in occasional service until 1861, when she was burned to avoid capture by the Confederates
USS Columbia (1862) was a captured Confederate screw steamer that ran aground in 1863
USS Columbia (1864) was an ironclad, also captured from the Confederates in 1865 and in use until June of that year.
USS Columbia (C-12), later CA-16, was a protected cruiser in service from 1894 to 1921. At the end of its career it was renamed USS Old Columbia.
USS Columbia (AG-9) was originally the Great Northern, a troop transport, renamed in 1921 and used until 1922
USS Columbia (CL-56) was a light cruiser launched 17 December 1941 and active throughout the rest of World War II
USS Columbia (AOT-182), a transport oiler, was returned to her owner on 1 May 1984
USS Columbia (SSN-771) is a Los Angeles-class submarine commissioned in 1995 and currently in active service
USS Columbia (SSBN-826) is the future lead ship of the Columbia-class submarine
See also
Columbia Rediviva
Columbia was the name of the Command Module on Apollo 11
Space Shuttle Columbia
HMCS Columbia