Suvarna Garge (Editor)

USP16

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Species
  
Entrez
  
10600

Human
  
Ensembl
  
ENSG00000156256

USP16

Aliases
  
USP16, UBP-M, UBPM, ubiquitin specific peptidase 16

External IDs
  
MGI: 1921362 HomoloGene: 38183 GeneCards: USP16

Ubiquitin carboxyl-terminal hydrolase 16 is an enzyme that in humans is encoded by the USP16 gene.

This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References

USP16 Wikipedia


Similar Topics