EC number 4.1.1.35 ExPASy NiceZyme view | CAS number 9024-68-4 | |
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In enzymology, an UDP-glucuronate decarboxylase (EC 4.1.1.35) is an enzyme that catalyzes the chemical reaction
Hence, this enzyme has one substrate, UDP-D-glucuronate, and two products, UDP-D-xylose and CO2.
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming). Other names in common use include uridine-diphosphoglucuronate decarboxylase, and UDP-D-glucuronate carboxy-lyase. This enzyme participates in starch and sucrose metabolism and nucleotide sugars metabolism. It employs one cofactor, NAD+.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2B69 and 2BLL.