UDP N acetylglucosamine 4,6 dehydratase (configuration retaining)

Updated on Dec 31, 2024

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EC number 4.2.1.135 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135, PglF) is an enzyme with systematic name UDP-N-acetyl-alpha-D-glucosamine hydro-lyase (configuration-retaining; UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose-forming). This enzyme catalyses the following chemical reaction

UDP-N-acetyl-alpha-D-glucosamine ⇌ UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + H₂O

This enzyme contains NAD⁺ as a cofactor.

References

UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) Wikipedia

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