UDP N acetyl 2 amino 2 deoxyglucuronate dehydrogenase

Updated on Dec 31, 2024

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EC number 1.1.1.335 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase (EC 1.1.1.335, WlbA, WbpB) is an enzyme with systematic name UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate:NAD⁺ 3-oxidoreductase. This enzyme catalyses the following chemical reaction:

UDP-N-acetyl-2-amino-2-deoxy-alpha-D-glucuronate + NAD⁺ ⇌ UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H⁺

This enzyme participates in the biosynthesis of lipopolysaccharide UDP-alpha-D-ManNAc3NAcA.

References

UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase Wikipedia

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