EC number 3.1.21.3 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 37263-09-5 BRENDA BRENDA entry KEGG KEGG entry | |
Type I site-specific deoxyribonuclease (EC 3.1.21.3, type I restriction enzyme, deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent), restriction-modification system, deoxyribonuclease (adenosine triphosphate-hydrolyzing), adenosine triphosphate-dependent deoxyribonuclease, ATP-dependent DNase, type 1 site-specific deoxyribonuclease) is an enzyme. This enzyme catalyses the following chemical reaction
Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolysedThey have an absolute requirement for ATP (or dATP) and S-adenosyl-L-methionine.
References
Type I site-specific deoxyribonuclease Wikipedia(Text) CC BY-SA