Tsutsui (written: 筒井 meaning "round well") is a Japanese surname. Notable people with the surname include:
Hajime Tsutsui (筒井 はじめ, born 1970), Japanese artist
Tsutsui Jōmyō Meishū (筒井 浄妙 明秀), Japanese warrior monk
Tsutsui Junkei (筒井 順慶, 1549–1584), Japanese daimyō
Tsutsui Junshō (筒井 順昭, 1523–1550), Japanese daimyō
Kazuya Tsutsui (筒井 和也, born 1981), Japanese baseball player
Mihoko Tsutsui (筒井 視穂子, born 1985), Japanese volleyball player
Nobutaka Tsutsui (筒井 信隆, born 1944), Japanese politician
Noriaki Tsutsui (筒井 紀章, born 1976), Japanese footballer
Ryohei Ron Tsutsui (born 1977), Japanese film producer
Tsutsui Sadatsugu (筒井 定次, 1562–1615), Japanese samurai
Shan Tsutsui (born 1971), American politician
William Tsutsui, American academic
Yasutaka Tsutsui (筒井 康隆, born 1934), Japanese writer and actor
