Trujillo is a surname. Notable people with the surname include:
Alex Trujillo (born 1974), Puerto Rican boxer
Alfonso López Trujillo (1935–2008), Colombian cardinal
César Gaviria Trujillo (born 1947), Colombian president
Chad Trujillo (born 1973), American astronomer
Diego Trujillo (born 1960), Colombian actor
Héctor Trujillo (1908–2002), Dominican Republic president
Justin Trujillo (born 1977), American Silent Activist
Luis Trujillo (born 1977), Peruvian footballer
María Trujillo (born 1959), Mexican–American athlete
Mariano Trujillo (born 1977), Mexican footballer
Rafael Trujillo (1891–1961), Dominican Republic president
Rafael Trujillo (sailor) (born 1975), Spanish sailor
Raoul Trujillo (born 1955), American actor
Rigoberto Trujillo (born 1978), Cuban judoka
Robert Trujillo (born 1964), American musician, member of Metallica
Solomon Trujillo (born 1951), American business executive
Stephen Trujillo, American soldier
Tony Trujillo (born 1982), American skateboarder
