Trost ligand

The Trost ligand is a chiral ligand pioneered by Barry Trost for use in the palladium-catalyzed Trost asymmetric allylic alkylation. Other C₂-symmetric ligands derived from trans-1,2-diaminocyclohexane (DACH) have also been developed by the Trost group, such as the (R,R)-DACH-naphthyl ligand derived from 2-diphenylphosphino-1-naphthalenecarboxylic acid. Related bidentate phosphine-containing ligands derived from other chiral diamines have also been developed for applications in asymmetric synthesis.