Girish Mahajan (Editor)

Trimethylthiazoline

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Appearance
  
Light yellow liquid

Trimethylthiazoline

Trimethylthiazoline (TMT or 2,5-dihydro-2,4,5-trimethylthiazoline) is a constituent of fox urine that is an innately aversive odor to rodents. The chemical is liquid at room temperature and has a very light yellow color which darkens on oxygen exposure over time.

Research

Researchers at SRQBio were able to synthesize TMT and use it with a combination of other stressors such as foot shocks/loud noises as a natural predator psychogenic stress to study posttraumatic stress disorder in rodents. TMT has been called an "innate threat stimulus" because of how it "induces a number of fear and defensive behaviors" in naive mice and rats.

References

Trimethylthiazoline Wikipedia