Trisha Shetty (Editor)

Trimethylsulfonium—tetrahydrofolate N methyltransferase

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EC number  2.1.1.19
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  37256-92-1
BRENDA  BRENDA entry
KEGG  KEGG entry

In enzymology, a trimethylsulfonium-tetrahydrofolate N-methyltransferase (EC 2.1.1.19) is an enzyme that catalyzes the chemical reaction

trimethylsulfonium + tetrahydrofolate dimethylsulfide + 5-methyltetrahydrofolate

Thus, the two substrates of this enzyme are trimethylsulfonium and tetrahydrofolate, whereas its two products are dimethyl sulfide and 5-methyltetrahydrofolate.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is trimethylsulfonium:tetrahydrofolate N-methyltransferase. This enzyme is also called trimethylsulfonium-tetrahydrofolate methyltransferase. This enzyme participates in one carbon pool by folate.

References

Trimethylsulfonium—tetrahydrofolate N-methyltransferase Wikipedia


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