Entrez 2618 | Ensembl n/a | |
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Aliases GART, AIRS, GARS, GARTF, PAIS, PGFT, PRGS, phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase External IDs OMIM: 138440 MGI: 95654 HomoloGene: 637 GeneCards: GART | ||
Trifunctional purine biosynthetic protein adenosine-3 is an enzyme that in humans is encoded by the GART gene.
This protein is a trifunctional polypeptide. It has Phosphoribosylamine—glycine ligase (EC 6.3.4.13), Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2), AIR synthetase (FGAM cyclase) (EC 6.3.3.1) activity which is required for de novo purine biosynthesis.
References
Trifunctional purine biosynthetic protein adenosine-3 Wikipedia(Text) CC BY-SA