Neha Patil (Editor)

Translocase

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Translocase is a general term for a protein that assists in moving another molecule, usually across a membrane. Translocases are the most common secretion system in Gram positive bacteria.

It is also a historical term for the protein now called elongation factor G, due to its function in moving the tRNA and mRNA through the ribosome.

Examples

  • ornithine translocase (SLC25A15), associated with ornithine translocase deficiency.
  • carnitine-acylcarnitine translocase (SLC25A20), associated with carnitine-acylcarnitine translocase deficiency.
  • Translocase of outer mitochondrial membrane 40 (TOMM40), a protein encoded by the TOMM40 gene, whose alleles differentially impact the risk for Alzheimer's disease

    • References

    Translocase Wikipedia
    (Text) CC BY-SA