Trans o hydroxybenzylidenepyruvate hydratase aldolase

Updated on Jan 01, 2025

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EC number 4.1.2.45 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

Trans-o-hydroxybenzylidenepyruvate hydratase-aldolase (EC 4.1.2.45, 2'-hydroxybenzalpyruvate aldolase, NsaE, tHBPA hydratase-aldolase) is an enzyme with systematic name (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate hydro-lyase. This enzyme catalyses the following chemical reaction

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H₂O ⇌ salicylaldehyde + pyruvate

This enzyme is involved in naphthalene degradation.

References

Trans-o-hydroxybenzylidenepyruvate hydratase-aldolase Wikipedia

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