Trans L 3 hydroxyproline dehydratase

In enzymology, a trans-L-3-hydroxyproline dehydratase (EC 4.2.1.77) is an enzyme that catalyzes the chemical reaction

trans-L-3-hydroxyproline ⇌ Delta₁-pyrroline 2-carboxylate + H₂O

Hence, this enzyme has one substrate, trans-L-3-hydroxyproline, and two products, Delta1-pyrroline 2-carboxylate and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is trans-L-3-hydroxyproline hydro-lyase (Delta1-pyrroline-2-carboxylate-forming). This enzyme is also called trans-L-3-hydroxyproline hydro-lyase.