Density 951 kg/m³ Appearance Colorless liquid Chemical formula C6H14N2 | Molar mass 114.19 g·mol−1 Pubchem 479307 | |
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Melting point 14 to 15 °C (57 to 59 °F; 287 to 288 K) Boiling point 79 to 81 °C (174 to 178 °F; 352 to 354 K) 15 mm Hg | ||
trans-1,2-Diaminocyclohexane is an organic compound with the formula C6H10(NH2)2. This diamine is a building block for chiral ligands that are useful in asymmetric catalysis.
A mixture of cis- and trans-1,2-diaminocyclohexane is produced by the hydrogenation of o-phenylenediamine. The racemic trans isomer [1:1 mixture of (1R,2R)-1,2-diaminocyclohexane and (1S,2S)-1,2-diaminocyclohexane] can be separated into the two enantiomers using enantiomerically pure tartaric acid as the resolving agent.
Derived ligands
Representative ligands prepared from (1R,2R)- or (1S,2S)-1,2-diaminocyclohexane are diaminocyclohexanetetraacetic acid (CyDTAH4), Trost ligand, and the salen analogue used in the Jacobsen epoxidation.
References
Trans-1,2-Diaminocyclohexane Wikipedia(Text) CC BY-SA