Thomas James (c. 1573–1629) was an English librarian.
Thomas James may also refer to:
Tom James (born 1984), rowerTom James (rugby player) (born 1987), Welsh rugby union footballerTom James (English footballer) (born 1988), English footballerTom James (Welsh footballer) (born 1996), Welsh footballerTommy James (American football) (1923–2007), American football cornerbackThomas James (fl.1414), MP for DunwichThomas James (died 1615), English politicianThomas Lemuel James (1831–1916), banker and journalist who served as U.S. Postmaster General in 1881Thomas James (sea captain) (1593–1635), English sea captainThomas James (minister) (1804–1891), former slave who wrote a short memoirThomas James (businessman), American businessman, chairman of Raymond JamesThomas Naum James (1925–2010), American cardiologistTommy James (born 1947), musicianT. G. H. James (1923–2009), British EgyptologistThomas James (bishop) (1786–1828), Anglican bishop in IndiaThomas Shadrach James (1859–1946), school teacher, Methodist lay preacher, linguist and herbalistTommy Lee James, American country music songwriter and record producer 