|Aliases TJP2, C9DUPq21.11, DFNA51, DUP9q21.11, PFIC4, X104, ZO2, Tight junction protein 2|
External IDs MGI: 1341872 HomoloGene: 3541 GeneCards: TJP2
Tight junction protein ZO-2 is a protein that in humans is encoded by the TJP2 gene.
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM]
Tight junction protein 2 has been shown to interact with Tight junction protein 1, Band 4.1 and Occludin.