Tickle is a surname. Notable people with the surname include:
Charlie Tickle (1883 – after 1919), English footballerCheryll Tickle, British biologistDanny Tickle (born 1983), English rugby league footballerDavid Tickle, British record producer and engineerGerard William Tickle (1909–1994), English prelateJon Tickle (born 1974), British TV presenterPhyllis Tickle (1934–2015), American author and lecturerSteven Ray Tickle, American television personality on Moonshiners and Tickle.