Tickle is a surname. Notable people with the surname include:
Charlie Tickle (1883 – after 1919), English footballer
Cheryll Tickle, British biologist
Danny Tickle (born 1983), English rugby league footballer
David Tickle, British record producer and engineer
Gerard William Tickle (1909–1994), English prelate
Jon Tickle (born 1974), British TV presenter
Phyllis Tickle (1934–2015), American author and lecturer
Steven Ray Tickle, American television personality on Moonshiners and Tickle.
