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Thyronamine

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Formula
  
C14H15NO2

Molar mass
  
229.274 g/mol

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Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).

Types

The group includes:

  • Thyronamine (T0AM)
  • 3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), an intracellular G protein-coupled receptor
  • 3,5-Diiodothyronamine (T2AM)
  • 3,5,3'-Triiodothyronamine (T3AM)

    • References

    Thyronamine Wikipedia
    (Text) CC BY-SA


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