Name Terence Rabbitts | Fields Molecular biology | |
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Institutions MRC Laboratory of Molecular BiologyUniversity of Oxford Notable awards Colworth Medal (1981)FRS (1987) [1]CIBA medal (1993) [2]FMedSci (1998) [3]Clotten Foundation Award (2015) Institution Laboratory of Molecular Biology, University of Oxford |
Terence Howard Rabbitts FRS FMedSci (born 17 June 1946) is currently Professor of Molecular Biology at the University of Oxford.
He was educated at John Ruskin Grammar School, the University of East Anglia (BSc) and the National Institute for Medical Research (PhD).
He pioneered the method of cDNA cloning, an approach universally used in bioscience and biotechnology, and elucidated the organization, diversity and rearrangement of human antibody genes, which defined the building blocks for construction of therapeutic antibody repertoires. He also pioneered chimaeric antibodies (with Michael Neuberger). He discovered the LMO and HOX11 chromosomal translocation families in T cell leukaemia and the first fusion gene in a solid tumour. He developed the first knock-in gene, now a widely employed approach in gene targeting and gene editing.
He was awarded the Colworth Medal in 1981, made a Fellow of the Royal Society in 1987. He was awarded the CIBA medal in 1993 [4] and made a Fellow of the Academy of Medical Sciences in 1998 [5] He was awarded the Clotten Foundation Prize in 2015.