|Champion Steffi Graf (FRG)|
Start date 1988
|Final score 6–3, 6–3|
|Runner-up Gabriela Sabatini (ARG)|
The Women's Singles competition was part of the tennis program at the 1988 Summer Olympics. Steffi Graf of West Germany defeated Gabriela Sabatini of Argentina in the gold medal match. By winning the gold medal, Steffi Graf finished off her "Calendar Golden Slam" having won all four Grand Slam tournaments and the Olympic gold medal in the same calendar year. Steffi had also beaten Sabatini earlier that summer in the final of the U.S. Open, thus capturing the final leg of the "Grand Slam".
All seeds received a bye to the second round.