Kalpana Kalpana

Telomestatin

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Pubchem  11954679
Telomestatin httpsuploadwikimediaorgwikipediacommons77

Telomestatin is a macrocyclic chemical compound that acts by inhibiting the telomerase activity of in vitro cancer cells. It was first isolated from the bacteria Streptomyces anulatus. Telomestatin induces the formation of basket-type G-quadruplex (G4) structures from hybrid-type G-quadruplexes in the telomeric region. Upon formation of G4 structure there will be a decrease in the activity of the telomerase, which is involved in the replication of the telomeres and as a result the cell dies due to Hayflick type senescence.

Telomestatin Interaction of Telomestatin with the Telomeric Singlestrand Overhang
Telomestatin Telomestatin Related Keywords amp Suggestions Telomestatin Long Tail
Telomestatin S Stereoisomer of telomestatin as a potent Gquadruplex binder and
Telomestatin FileTelomestatin3Dballspng Wikimedia Commons
Telomestatin

References

Telomestatin Wikipedia


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