Suvarna Garge

Taxadiene synthase

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EC number  4.2.3.17
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  169277-52-5
BRENDA  BRENDA entry
KEGG  KEGG entry

In enzymology, a taxadiene synthase (EC 4.2.3.17) is an enzyme that catalyzes the chemical reaction

geranylgeranyl diphosphate taxa-4,11-diene + diphosphate

Hence, this enzyme has one substrate, geranylgeranyl diphosphate, and two products, taxa-4,11-diene and diphosphate.

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxa-4,11-diene-forming). Other names in common use include geranylgeranyl-diphosphate diphosphate-lyase (cyclizing,, and taxadiene-forming). This enzyme participates in diterpenoid biosynthesis.

References

Taxadiene synthase Wikipedia


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