Rahul Sharma (Editor)

Tartronate semialdehyde synthase

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EC number
  
4.1.1.47

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
9027-24-1

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a tartronate-semialdehyde synthase (EC 4.1.1.47) is an enzyme that catalyzes the chemical reaction

2 glyoxylate tartronate semialdehyde + CO2

Hence, this enzyme has one substrate, glyoxylate, and two products, tartronate semialdehyde and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is glyoxylate carboxy-lyase (dimerizing tartronate-semialdehyde-forming). Other names in common use include tartronate semialdehyde carboxylase, glyoxylate carbo-ligase, glyoxylic carbo-ligase, hydroxymalonic semialdehyde carboxylase, tartronic semialdehyde carboxylase, glyoxalate carboligase, and glyoxylate carboxy-lyase (dimerizing). This enzyme participates in glyoxylate and dicarboxylate metabolism. It has 2 cofactors: FAD, and Thiamin diphosphate.

References

Tartronate-semialdehyde synthase Wikipedia


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