Talmadge is a surname. Notable people with the surname include:
Constance Talmadge (1897–1973), American actress, sister of Norma and Natalie
Eugene Talmadge (1884–1946), American politician
Herman Talmadge (1913–2002), American politician, son of Eugene
Natalie Talmadge (1896–1969), American actress
Norma Talmadge (1893–1957), American actress
Madeleine Talmadge Force (1893–1940), Titanic survivor, widow of Col. John Jacob Astor IV
Phil Talmadge, Washington State Supreme Court justice
Richard Talmadge (1892–1981), American actor, stuntman and film director
Talmadge Hayer, convicted assassin of Malcolm X