Takeshita (written: 竹下), sometimes romanized as Takishita, is a Japanese surname. People with the name include:
Isamu Takeshita (1869–1949), admiral in the Imperial Japanese Navy
Keiko Takeshita (born 1953), Japanese actress
Konosuke Takeshita (born 1995), Japanese professional wrestler
Kōshi Takeshita (born 1964), Japanese photographer
Lt. Col. Masahiko Takeshita, head of the domestic affairs section of the Military Affairs Bureau of the Imperial Japanese Army during World War II
Noboru Takeshita (1924–2000), 74th Prime Minister of Japan
Rena Takeshita (born 1981), Japanese fashion model / actress
Wataru Takeshita (born 1946), Japanese politician
Yoshie Takeshita (born 1978), Japanese volleyball player
Yuriko Takeshita (born 1988), Japanese slalom canoer