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Tagatose 6 phosphate kinase

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EC number
  
2.7.1.144

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
39434-00-9

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

In enzymology, a tagatose-6-phosphate kinase (EC 2.7.1.144) is an enzyme that catalyzes the chemical reaction

ATP + D-tagatose 6-phosphate ADP + D-tagatose 1,6-bisphosphate

Thus, the two substrates of this enzyme are ATP and D-tagatose 6-phosphate, whereas its two products are ADP and D-tagatose 1,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-tagatose-6-phosphate 1-phosphotransferase. This enzyme participates in galactose metabolism.

Structural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes 2AWD, 2F02, 2JG1, 2JGV, and 2Q5R.

References

Tagatose-6-phosphate kinase Wikipedia