Puneet Varma (Editor)

TWIST2

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Species
  
Human

Entrez
  
117581

Human
  
Mouse

Ensembl
  
ENSG00000233608

Aliases
  
TWIST2, DERMO1, FFDD3, SETLSS, bHLHa39, AMS, BBRSAY, twist family bHLH transcription factor 2

External IDs
  
MGI: 104685 HomoloGene: 40594 GeneCards: TWIST2

Twist-related protein 2 is a protein that in humans is encoded by the TWIST2 gene.

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Twist. It is thought that during osteoblast development this protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype.

Interactions

TWIST2 has been shown to interact with SREBF1.

References

TWIST2 Wikipedia