TRNA (adenine22 N1) methyltransferase

Updated on Dec 31, 2024

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EC number 2.1.1.217 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

TRNA (adenine²²-N¹)-methyltransferase (EC 2.1.1.217, TrmK, YqfN, Sp1610 (gene), tRNA: m1A22 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine²²-N¹)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + adenine²² in tRNA ⇌ S-adenosyl-L-homocysteine + N¹-methyladenine²² in tRNA

The enzyme specifically methylates adenine²² in tRNA.

References

TRNA (adenine22-N1)-methyltransferase Wikipedia

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