Suvarna Garge (Editor)

TRNA (cytosine38 C5) methyltransferase

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EC number
  
2.1.1.204

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

TRNA (cytosine38-C5)-methyltransferase (EC 2.1.1.204, hDNMT2 (gene), DNMT2 (gene), TRDMT1 (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytosine38-C5)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytosine38 in tRNA ⇌ S-adenosyl-L-homocysteine + 5-methylcytosine38 in tRNA

The eukaryotic enzyme catalyses methylation of cytosine38 in the anti-codon loop of tRNAAsp(GTC), tRNAVal(AAC) and tRNAGly(GCC).

References

TRNA (cytosine38-C5)-methyltransferase Wikipedia
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