Supriya Ghosh (Editor)

TRNA (cytosine34 C5) methyltransferase

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EC number
  
2.1.1.203

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

TRNA (cytosine34-C5)-methyltransferase (EC 2.1.1.203, hTrm4 Mtase, hTrm4 methyltransferase, hTrm4 (gene), tRNA:m5C-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (cytosine34-C5)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + cytosine34 in tRNA precursor ⇌ S-adenosyl-L-homocysteine + 5-methylcytosine34 in tRNA precursor

The human enzyme is specific for C5-methylation of cytosine34 in tRNA precursors.

References

TRNA (cytosine34-C5)-methyltransferase Wikipedia
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