TRNA (adenine58 N1) methyltransferase

Updated on Nov 27, 2023

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EC number 2.1.1.220 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

TRNA (adenine⁵⁸-N¹)-methyltransferase (EC 2.1.1.220, tRNA m1A58 methyltransferase, tRNA (m1A58) methyltransferase, TrmI, tRNA (m1A58) Mtase, Rv2118cp, Gcd10p-Gcd14p, Trm61p-Trm6p) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine⁵⁸-N¹)-methyltransferase. This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + adenine⁵⁸ in tRNA ⇌ S-adenosyl-L-homocysteine + N¹-methyladenine⁵⁸ in tRNA

The enzyme specifically methylates adenine⁵⁸ in tRNA.

References

TRNA (adenine58-N1)-methyltransferase Wikipedia

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