Neha Patil (Editor)

TRIM69

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
Species
  
Human

Entrez
  
140691

Human
  
Mouse

Ensembl
  
n/a

Aliases
  
TRIM69, HSD-34, HSD34, RNF36, Trif, tripartite motif containing 69

External IDs
  
MGI: 1918178 HomoloGene: 18827 GeneCards: TRIM69

Tripartite motif containing 69 is a protein that in humans is encoded by the TRIM69 gene.

Function

This gene encodes a member of the RING-B-box-coiled-coil (RBCC) family and encodes a protein with an N-terminal RING finger motif, a PRY domain and a C-terminal SPRY domain. The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and, when overexpressed, induces apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

References

TRIM69 Wikipedia