Suvarna Garge (Editor)

TPTE

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Covid-19
External IDs  GeneCards: TPTE
Human  Mouse
Ensembl  ENSG00000274391
Species  Human
Entrez  7179
Aliases  TPTE, CT44, PTEN2, transmembrane phosphatase with tensin homology

Putative tyrosine-protein phosphatase TPTE is an enzyme that in humans is encoded by the TPTE gene.

Function

TPTE is a member of a large class of membrane-associated phosphatases with substrate specificity for the 3-position phosphate of inositol phospholipids. TPTE is believed to lack phosphatase activity; however, the closely related protein TPIP, also called TPTE2 is an active phosphatase with activity against inositol phospholipid substrates. TPTE and TPIP are the mammalian homologues to the family of voltage sensitive phosphatases.

References

TPTE Wikipedia


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