Species Human Entrez 8995 | Human Mouse Ensembl ENSG00000120337 | |
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Aliases TNFSF18, AITRL, GITRL, TL6, hGITRL, TNLG2A, tumor necrosis factor superfamily member 18 External IDs MGI: 2673064 HomoloGene: 3732 GeneCards: TNFSF18 | ||
Tumor necrosis factor ligand superfamily member 18 is a protein that in humans is encoded by the TNFSF18 gene.
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
References
TNFSF18 Wikipedia(Text) CC BY-SA