Species Human Entrez 51330 | Human Mouse Ensembl ENSG00000006327 | |
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Aliases TNFRSF12A, CD266, FN14, TWEAKR, tumor necrosis factor receptor superfamily member 12A External IDs MGI: 1351484 HomoloGene: 8451 GeneCards: TNFRSF12A | ||
Tumor necrosis factor receptor superfamily member 12A also known as the TWEAK receptor (TWEAKR) is a protein that in humans is encoded by the TNFRSF12A gene.
Clinical significance
NFAT1 regulates the expression of TWEAKR (this protein) and its ligand TWEAK with lipocalin 2 to increase breast cancer cell invasion.
References
TNFRSF12A Wikipedia(Text) CC BY-SA