Species Human Entrez 51643 | Human Mouse Ensembl n/a | |
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Aliases TMBIM4, GAAP, LFG4, S1R, ZPRO, CGI-119, transmembrane BAX inhibitor motif containing 4 External IDs MGI: 1915462 HomoloGene: 56740 GeneCards: TMBIM4 | ||
Transmembrane BAX inhibitor motif-containing protein 4 is a protein that in humans is encoded by the TMBIM4 gene. It is also known as Golgi anti-apoptotic protein (GAAP) due to its function.
Function
GAAP is a protein present in the Golgi body of a cell that helps regulate apoptosis, a form of programmed cell death. By regulating the fluxes of Ca+2, an increase of GAAP can help prevent apoptosis.
References
TMBIM4 Wikipedia(Text) CC BY-SA