Supriya Ghosh (Editor)

TM 38837

Updated on
Edit
Like
Comment
Share on FacebookTweet on TwitterShare on LinkedInShare on Reddit
ATC code
  
none

PubChem CID
  
49779607

3D model (Jmol)
  
Interactive image

Pubchem
  
49779607

CAS Number
  
1253641-65-4

Formula
  
C30H25Cl2F3N4OS

Molar mass
  
617.51 g/mol

ChemSpider ID
  
29361353

TM-38837 httpsuploadwikimediaorgwikipediacommonsthu

TM-38837 is a small molecule inverse agonist/antagonist of the CB1 cannabinoid receptor, with peripheral selectivity. It is being developed for the treatment of obesity and metabolic disorders by 7TM Pharma. The company has announced phase I clinical trials.

TM-38837 is among the first of a new generation of cannabinoid receptor antagonist designed to avoid the central nervous system liabilities of the first generation CB1 receptor antagonists such as rimonabant.

References

TM-38837 Wikipedia