Species Human Entrez 7049 | Human Mouse Ensembl ENSG00000069702 | |
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Aliases TGFBR3, BGCAN, betaglycan, transforming growth factor beta receptor 3 External IDs OMIM: 600742 MGI: 104637 HomoloGene: 2436 GeneCards: TGFBR3 | ||
Betaglycan also known as Transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan >300 kDa in molecular weight. Betaglycan binds to various members of the TGF-beta superfamily of ligands via its core protein, and bFGF via its heparan sulfate chains. It is not involved directly in TGF-beta signal transduction but by binding to various member of the TGF-beta superfamily at the cell surface it acts as a reservoir of ligand for TGF-beta receptors.
References
TGFBR3 Wikipedia(Text) CC BY-SA