Species Human Entrez 7006 | Human Mouse Ensembl ENSG00000135605 | |
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Aliases TEC, PSCTK4, tec protein tyrosine kinase External IDs MGI: 98662 HomoloGene: 1302 GeneCards: TEC | ||
Tyrosine-protein kinase Tec is an enzyme that in humans is encoded by the TEC gene.
Contents
Function
The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein-coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Interactions
TEC (gene) has been shown to interact with:
References
TEC (gene) Wikipedia(Text) CC BY-SA